内皮 - 间充质转化相关通路创面愈合方面的研究进展

彦庚 赵(中医国家临床医学研究中心疮疡及周围血管外科，中国;)
阳 徐(中医国家临床医学研究中心疮疡及周围血管外科，中国;)

摘要

长期以来，促进创面愈合一直是医学领域的重要课题，其中，血管生成及血管重组是创面愈合的关键。内皮-间充质转化（Endothelial-to-Mesenchymal Transition，简称EndMT）在血管生成及血管重组中占据重要地位，是近十几年来的研究热点。该文综合剖析了EndMT的相关信号通路及其在创面愈合中的作用，旨在阐释创面愈合中EndMT的发生与发展过程，并通过采纳更为有潜力的治疗策略来指导临床实践，从而提升临床中EndMT相关的治疗效果，推动创面愈合领域的持续发展。

关键词

内皮；间充质转化；创面愈合；血管

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DOI: http://dx.doi.org/10.12345/yzlcyxzz.v9i3.37311