氨甲环酸对创伤性凝血病患者凝血功能及预后的病理生理机制探索

成远 毛(贵州医科大学附属金阳医院，中国)

摘要

目的：分析氨甲环酸注射液对创伤性凝血病患者凝血功能及预后的病理生理机制。方法：选择2024年1月至2025年6月间我院收治的创伤性凝血病患者60例作为本次研究的对象，采用随机数表法分组，分为对照组（30例，常规治疗）与观察组（30例，氨甲环酸注射液治疗），比较两组凝血功能及预后情况。结果：观察组在凝血酶原时间（PT）、活化部分凝血活酶时间（APTT）、纤维蛋白原（FIB）及D-二聚体（D-D）水平方面明显优于对照组；观察组在输血量、住院天数及MODS发生率（多器官功能障碍综合征）等预后指标方面优于对照组（P＜0.05）。结论：氨甲环酸注射液在创伤性凝血病患者的治疗中具有良好的应用效果，能够显著改善凝血功能指标，有助于减少输血量、缩短住院时间，降低MODS发生率，提升整体临床有效率，在今后干预中值得推广。

关键词

氨甲环酸注射液;创伤性凝血病;凝血功能;预后效果；病理生理机制

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DOI: http://dx.doi.org/10.12345/yzlcyxzz.v8i7.30114