基底细胞癌治疗与预后恶化的研究进展

荣 贵(赣南医科大学，中国)
振 黄(赣南医科大学，中国)
龙年 李(赣南医科大学，中国)
春雷 万(赣南医科大学，中国)

摘要

基底细胞癌（BCC）作为临床最常见的皮肤恶性肿瘤，早期规范治疗后预后良好。然而，局部晚期、侵袭性亚型及转移性病例仍面临治疗手段有限、预后恶化风险高的临床困境。本文系统综述了当前BCC治疗领域的最新进展，深入剖析了导致预后恶化的关键危险因素，旨在为临床优化治疗策略、改善患者预后提供参考依据。

关键词

基底细胞癌；治疗进展；预后危险因素

参考

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e has become a cornerstone measure for preventing nosocomial infections in critical departments like ICUs. Traditional hand hygiene management relied on manual inspections, resulting in inadequate supervision. In recent years, the clinical implementation

of intelligent hand hygiene monitoring systems—featuring automatic sensing, identity verification, and data analytics—has significantly improved compliance rates and reduced infection rates. Using a tertiary hospital’s ICU as a case study, this paper systematically evaluates the effectiveness of smart hand hygiene systems through pre-post controls and cost-benefit analysis. Results demonstrate

that these systems not only substantially enhance hand hygiene adherence and infection prevention outcomes but also offer notable cost efficiency. The study further proposes technical optimizations, staff training programs, and process reengineering strategies, providing act

ionable insights for smart healthcare facilities and medical management decision-making. KeywordsIntelligent hand hygiene; Hospital infection control; ICU; Compliance rate; Cost-effectiveness; Smart healthcare智能手卫生监测系统在综合 ICU 院感防控中的应用效果及成本效益分析赵以娟海东市第二人民医院，中国·青海海东 810799摘要随着医院感染防控标准的提升，手卫生已成为预防ICU等重点科室院感的核心措施。传统手卫生依赖人工巡查，监督不够全面。近年来，智能手卫生监测系统在临床推广，通过自动感应、身份识别和数据分析，有效提升了手卫生依从率，降低了医院感染率。本文以某三甲医院ICU为例，采用前后对照与成本效益分析，系统评估智能手卫生系统的应用效果。结果显示，该系统不仅显著提升了手卫生依从率和院感防控成效，还具有较高的经济性。文章进一步提出了技术优化、人员培训与流程再造等建议，为智慧医院和医疗管理决策提供参考。关键词智能手卫生；医院感染防控；ICU；依从率；成本效益；智慧医疗【作者简介】赵以娟（1990-），女，中国青海人，本科，主管护师，从事医院感染管理研究。1 引言医院感染作为影响住院患者安全和医疗质量的突出问题，尤以综合ICU等高风险病区为甚。ICU患者病情危重、侵入性操作多、抗生素使用频繁，易成为耐药菌繁殖和传播的高发场所。手卫生被世界卫生组织（WHO）和中国《医院感染管理规范》公认为最重要、最直接、最具成本效益的院感防控措施。然而，在实际临床操作中，传统手卫生依从率受限于人员主观能动性、工作负荷与管理方式，导致合格率长期低于标准要求，成为医院感染防控短板。为突破手卫生管理瓶颈，近年来，智能手卫生监测系统作为信息化、自动化和精细化管理手段，逐渐在国内外重点科室推广应用。本文以ICU为对象，深入分析智能手卫生监测系统的功能机制、实施成效和成本效益，探讨其在综合医院感染防控中的价值，并提出优化策略，以期为智慧医院建设和院感精细化管理提供可借鉴经验。

DOI: http://dx.doi.org/10.12345/yzlcyxzz.v8i9.31976