苯磺酸瑞马唑仑联合阿芬太尼在老年患者无痛胃镜诊疗中的临床价值分析

福旺 姚(山东第二医科大学附属医院，中国)
栋 高(山东第二医科大学附属医院，中国)
琴 祝(山东第二医科大学附属医院，中国)

摘要

目的：探讨瑞马唑仑联合阿芬太尼在老年患者无痛胃镜诊疗中的应用价值，系统观察其临床实践效果。方法：以本院行无痛胃镜检查的180例老年患者为研究对象。采用随机数字表法分为实验组和对照组，各90例，比较两组T0、T1、T2、T3、T4、T5时刻的平均动脉压、心率、脉搏血氧饱和度（T1为平静吸氧 5min 后，T2为内镜通过喉部即刻、T3为麻醉诱导完成后 10min、T4为镜检结束即刻、T5为出室即刻）,以及患者睫毛反射消失时间，胃镜持续时间，停药后患者意识恢复时间，恢复室停留时间,患者不良反应发生情况。结果：T0时，两组MAP、心率、血氧饱和度比较，无统计学差异（P＞0.05）；T1、T2、T3、T4、T5时刻两组患者平均动脉压、心率水平均低于T0时刻，血氧饱和度比较无统计学差异。T1、T2、T4实验组平均动脉压、心率均高于对照组（P<0.05）；T2时两组MAP比较，无统计学差异（P＞0.05），但对照组心率高于实验组（P<0.05）；T5时两组MAP、心率水平均低于T0时刻，但实验组与对照组比较，无统计学差异（P＞0.05）。两组个时间点SpO2比较，无统计学差异（P＞0.05）。实验组睫毛反射消失时间及停药后意识恢复时间短于对照组（P＞0.05），两组胃镜持续时间及恢复室停留时间无统计学差异（P>0.05）。两组注射痛发生率比较具有统计学差异，实验组明显低于对照组（P＞0.05），其余不良反应发生率则无统计学差异（P>0.05）。结论：瑞马唑仑联合阿芬太尼应用于老年患者无痛胃镜检查，具有麻醉诱导迅速、术后苏醒快速、血流动力学状态相对稳定及注射痛发生率低等优势，临床应用价值显著。

关键词

老年患者；无痛胃镜；瑞马唑仑；血流动力学

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DOI: http://dx.doi.org/10.12345/yzlcyxzz.v9i2.36517